Role of vitamin D deficiency in systemic lupus erythematosus incidence and aggravation
نویسندگان
چکیده
منابع مشابه
Vitamin D deficiency in a patient with systemic lupus erythematosus.
OBJECTIVES Hypovitaminosis D is common in the general population. Many studies that have been conducted to show the association between vitamin D deficiency and systemic lupus erythematosus (SLE) reveal that deficiencies in vitamin D are common in this group of patients. Our aim was to study the relationship between 25(OH)D and disease activity in patients with SLE. METHODS Retrospective coho...
متن کاملVitamin D deficiency in Saudi patients with systemic lupus erythematosus.
OBJECTIVE To determine vitamin D status among Saudi patients with systemic lupus erythematosus (SLE) versus matched control group. METHODS Hospital-based cohorts of 165 SLE patients and 214 SLE-free volunteers were recruited at King Abdulaziz University Hospital in Jeddah, Kingdom of Saudi Arabia between January 2006 and June 2008. Serum levels of 25-hydroxyvitamin D [25(OH)D] were measured. ...
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Vitamin D is a steroid hormone that in addition to its well known role in the metabolism of calcium and phosphorus exerts immunoregulatory properties. Data from animal studies and from prospective clinical trials on patients with rheumatoid arthritis, multiple sclerosis and type 1 diabetes point to the potential role of vitamin D as important environmental factor in the development of autoimmun...
متن کاملNeurobrucellosis in systemic lupus erythematosus
Background: Brucellosis is a zoonotic infection which is endemic in many countries. It is a multisystem disease which may present with a broad spectrum of clinical manifestations and complications. Neurobrucellosis is an uncommon complication of brucellosis. Case presentation: A 25-year-old woman with a history of lupus for 5 months referred to the emergency ward of Shahid Beheshti Hosp...
متن کاملInfluence of vitamin D on cell cycle, apoptosis, and some apoptosis related molecules in systemic lupus erythematosus
Objective(s):Genetic and environmental factors are involved in the pathogenesis of systemic lupus erythematosus (SLE). Autoreactive lymphocytes are cleared through apoptosis and any disturbance in the apoptosis or clearance of apoptotic cells may disturb tolerance and lead to autoimmunity. Vitamin D has anti-proliferative effects and controls cell cycle progression. In this study we investigate...
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ژورنال
عنوان ژورنال: Autoimmunity Highlights
سال: 2017
ISSN: 2038-0305,2038-3274
DOI: 10.1007/s13317-017-0101-x